Quality control in mass spectrometry-based proteomics
نویسندگان
چکیده
منابع مشابه
Computational quality control tools for mass spectrometry proteomics.
As mass-spectrometry-based proteomics has matured during the past decade, a growing emphasis has been placed on quality control. For this purpose, multiple computational quality control tools have been introduced. These tools generate a set of metrics that can be used to assess the quality of a mass spectrometry experiment. Here we review which types of quality control metrics can be generated,...
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SUMMARY Quality control in mass spectrometry-based proteomics remains subjective, labor-intensive and inconsistent between laboratories. We introduce Metriculator, a software designed to facilitate long-term storage of extensive performance metrics as introduced by NIST in 2010. Metriculator features a web interface that generates interactive comparison plots for contextual understanding of met...
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The increasing number of biomedical and translational applications in mass spectrometry-based proteomics poses new analytical challenges and raises the need for automated quality control systems. Despite previous efforts to set standard file formats, data processing workflows and key evaluation parameters for quality control, automated quality control systems are not yet widespread among proteo...
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ژورنال
عنوان ژورنال: Mass Spectrometry Reviews
سال: 2017
ISSN: 0277-7037
DOI: 10.1002/mas.21544